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À propos de : Lipid Bilayers, NMR Relaxation,and Computer Simulations        

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  • Lipid Bilayers, NMR Relaxation,and Computer Simulations
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  • Brownian and molecular dynamics simulations of a lipid bilayerare described, and the calculated frequency-dependent 13C NMRT1 relaxation times are compared with experiment. A consistentmodel emerges. Through fast internal motions, individual lipidsaverage themselves into relatively cylindrical shapes on the 100 pstime scale and “wobble” in a cone-like potential on the nanosecondtime scale. These motions take place in a highly fluid environment,much like a liquid alkane. Lateral diffusion of the lipids is on asignificantly longer time scale because of restrictions at the bilayer/water interface, not because the interior of the bilayer is highlyviscous.
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