| Abstract
| - A tandem quadrupole ion trap/ion mobility spectrometer(QIT/IMS) has been constructed for structural analysisbased on the gas-phase mobilities of mass-selected ions.The instrument combines the ion accumulation, manipulation, and mass-selection capabilities of a modified iontrap mass spectrometer with gas-phase electrophoreticseparation in a custom-built ion mobility drift cell. Thequadrupole ion trap may be operated as a conventionalmass spectrometer, with ion detection using an off-axisdynode/multiplier arrangement, or as an ion source forthe IMS drift cell. In the latter case, pulses of ions areejected from the trap and transferred to the drift cell wheremobility in the presence of helium buffer gas is determined by the collision cross section of the ion. Ionstraversing the drift cell are detected by an in-line electronmultiplier and the data processed with a multichannelscaler. Preliminary data are presented on instrumentalperformance characteristics and the application of QIT/IMS to structural and conformational studies of aromaticions and protonated amine/crown ether noncovalentcomplexes generated via ion/molecule reactions in the iontrap.
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