| Abstract
| - Recently, it has been found that room-temperature ionicliquids can be used as stable, unusual selectivity stationary phases. They show “dual nature” properties, in thatthey separate nonpolar compounds as if they are nonpolarstationary phases and separate polar compounds as if theyare polar stationary phases. Extending ionic liquids to therealm of chiral separations can be done in two ways: (1)a chiral selector can be dissolved in an achiral ionic liquid,or (2) the ionic liquid itself can be chiral. There is a singleprecedent for the first approach, but nothing has beenreported for the second approach. In this work, wepresent the first enantiomeric separations using chiralionic liquid stationary phases in gas chromatography.Compounds that have been separated using these ionicliquid chiral selectors include alcohols, diols, sulfoxides,epoxides, and acetylated amines. Because of the syntheticnature of these chiral selectors, the configuration of thestereogenic center can be controlled and altered formechanistic studies and reversing enantiomeric retention.
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