Abstract
| - Bioprocessors for concentrating bioparticles, such as cellsand molecules, are commonly needed in bioanalysissystems. In this microfluidic processor, a global flow fieldgenerated by ac electroosmosis transports the embeddedparticles to the regions near the electrode surface. Theprocessor then utilizes electrophoretic and dielectrophoretic forces, which are effective in short range, to trapthe target cells and molecules on the electrode surface.By optimizing the operating parameters, we have concentrated various biological objects in a large range of sizes,including Escherichia coli bacteria, λ phage DNA, andsingle-stranded DNA fragments as small as 20 bases thathave a radius of gyration of only 3 nm.
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