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Site-directed alterations to the geometry of the aspartate transcarbamoylase zinc domain: Selective alteration to regulation by heterotropic ligands, isoelectric point, and stability in urea
Properties of a high-potential flavin analog and its use as an active site probe with clostridial flavodoxin
Complete nucleotide sequence of the antithrombin gene: Evidence for homologous recombination causing thrombophilia
Multiple protein-binding domains and functional cis-elements in the 5'-flanking region of the human pyruvate dehydrogenase .alpha.-subunit gene
The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A
Mechanism of intercalation into the DNA double helix by ethidium
Characterization of iron(II).cntdot.bleomycin-mediated RNA strand scission
Characterization of mutations in the cytochrome b subunit of the bc1 complex of Rhodobacter sphaeroides that affect the quinone reductase site (Qc)
Structure-function relationship of a recombinant human galactoside-binding protein
Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles
Pulmonary surfactant-associated protein SP-B has little effect on acyl chains in dipalmitoylphosphatidylcholine dispersions
Structural and sequence elements required for the self-cleaving activity of the hepatitis delta virus ribozyme
A new kinetic model for the steady-state reactions of the quinoprotein methanol dehydrogenase from Paracoccus denitrificans
Molecular dynamics simulations of the unfolding of apomyoglobin in water
GC base sequence recognition by oligoimidazolecarboxamide and C-terminus-modified analogs of distamycin deduced from circular dichroism, proton nuclear magnetic resonance, and methidiumpropylethylenediaminetetraacetate-iron(II) footprinting studies
Identification of specific contacts in T3 RNA polymerase-promoter interactions: Kinetic analysis using small synthetic promoters
Effect of sodium and nucleotide on the stability of solubilized calcium-free calcium-ATPase from scallop sarcoplasmic reticulum
Functionally important domains of the large hydrophilic loop of CP47 as probed by oligonucleotide-directed mutagenesis in Synechocystis sp. PCC 6803
Direct evidence for the exploitation of an .alpha.-helix in the catalytic mechanism of triosephosphate isomerase
Three-state denaturation of DnaK induced by guanidine hydrochloride. Evidence for an expandable intermediate
Cloning, sequencing, and expression in Escherichia coli of the gene coding for malate dehydrogenase of the extremely halophilic archaebacterium Haloarcula marismortui
Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: Intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine
Transforming the Escherichia coli Trp repressor into a site-specific nuclease
Carbon-13 NMR study of the effects of mutation on the tryptophan dynamics in chymotrypsin inhibitor 2: correlations with structure and stability. [Erratum to document cited in CA118(5):34967r]
Structure, 5'-flanking sequence, and chromosome location of the human N-formyl peptide receptor gene. A single-copy gene comprised of two exons on chromosome 19q.13.3 that yields two distinct transcripts by alternative polyadenylation
The acidic phosphoproteins from Saccharomyces cerevisiae ribosomes. Amino terminal acetylation is a conserved difference between P1 and P2 proteins
Tests of a model for promoter recognition by T7 RNA polymerase: Thymine methyl group contacts
Kinetic analysis of T7 RNA polymerase transcription initiation from promoters containing single-stranded regions
Comprehensive explanation of the anomalous EPR spectra of wild-type and mutant cytochrome c peroxidase compound ES
Masthead
Three-dimensional structure of tyrosine phenol-lyase
Molecular mechanisms regulating the production of collagenase and TIMP in U937 cells: Evidence for involvement of delayed transcriptional activation and enhanced mRNA stability
Structural study of the sugar chains of CD36 purified from bovine mammary epithelial cells: Occurrence of novel hybrid-type sugar chains containing the Neu5Ac.alpha.2.fwdarw.6GalNAc.beta.1.fwdarw.4GlcNAc and the Man.alpha.1.fwdarw.2Man.alpha.1.fwdarw.3Man.alpha.1.fwdarw.6Man groups
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation
Engineered disulfide bonds as probes of the folding pathway of barnase: Increasing the stability of proteins against the rate of denaturation
Site-directed conversion of cysteine-565 to serine in PsaB of photosystem I results in the assembly of iron-sulfur [3Fe-4S] and iron-sulfur [4Fe-4S] clusters in Fx. A mixed-ligand iron-sulfur [4Fe-4S] cluster is capable of electron transfer to FA and FB
Mechanisms of mutation by oxidative DNA damage: Reduced fidelity of mammalian DNA polymerase .beta.
The DNA strand in DNA.cntdot.RNA hybrid duplexes is neither B-form nor A-form in solution
Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site
Analysis of enzyme specificity by multiple substrate kinetics
Investigation of a new copper-zinc superoxide dismutase mutant: The Thr .fwdarw. Arg 137 derivative
Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatases
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