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A Dynamic Structure for the Acyl−Enzyme Species of the Antibiotic Aztreonamwith the Citrobacter freundii β-Lactamase Revealed by Infrared Spectroscopy andMolecular Dynamics Simulations
Characterization of Rhodopsin Congenital Night Blindness Mutant T94I
Kinetic and Docking Studies of the Interaction of Quinones with the QuinoneReductase Active Site
Cytoplasmic Truncation of Glycoprotein Ibα Weakens Its Interaction with vonWillebrand Factor and Impairs Cell Adhesion
Evaluation of a Modular Strategy for the Construction of Novel Polydactyl ZincFinger DNA-Binding Proteins
Distinct Effects on Heparan Sulfate Structure by Different Active Site Mutations inNDST-1
B-Side Charge Separation in Bacterial Photosynthetic Reaction Centers: Nanosecond Time Scale Electron Transfer from HB- to QB
Potentiometric Analysis of UDP-Galactopyranose Mutase: Stabilization of theFlavosemiquinone by Substrate
Thermal and Urea-Induced Unfolding of the Marginally Stable Lac RepressorDNA-Binding Domain: A Model System for Analysis of Solute Effects on ProteinProcesses
Implications for RNase L in Prostate Cancer Biology
A Novel Modeling Protocol for Protein Receptors Guided by Bound-LigandConformation
Conformational Dynamics of DnaB Helicase upon DNA and Nucleotide Binding: Analysis by Intrinsic Tryptophan Fluorescence Quenching,
Nardilysin Cleaves Peptides at Monobasic Sites
Tau Polymerization: Role of the Amino Terminus
Factors that Contribute to Efficient Catalytic Activity of a Small Ca2+-DependentDeoxyribozyme in Relation to Its RNA Cleavage Function
Solution X-ray Scattering Data Show Structural Differences among Chimeras ofYeast and Chicken Calmodulin: Implications for Structure and Function
An Opsin Mutant with Increased Thermal Stability
The Function of the Chloride Ion in Photosynthetic Oxygen Evolution
Structural and Kinetic Analysis of Catalysis by a Thiamin Diphosphate-DependentEnzyme, Benzoylformate Decarboxylase
Global Structure and Dynamics of Human Apolipoprotein CII in Complex withMicelles: Evidence for Increased Mobility of the Helix Involved in the Activationof Lipoprotein Lipase,
Retinyl Esters Are the Substrate for Isomerohydrolase
Catalytic and Regulatory Domains of Doublecortin Kinase-1
Powering DNA Repair through Substrate Electrostatic Interactions
Understanding Copper Trafficking in Bacteria: Interaction between the CopperTransport Protein CopZ and the N-Terminal Domain of the Copper ATPase CopAfrom Bacillus subtilis
The Electron Transfer Complexes of Cytochrome c Peroxidase fromParacoccus denitrificans
Stimulation of DNA Strand Slippage Synthesis by a Bulge Binding SyntheticAgent
Catalysis of Diaphorase Reactions by Mycobacterium tuberculosis LipoamideDehydrogenase Occurs at the EH4 Level
Catalytic Strategy of S-Adenosyl-l-homocysteine Hydrolase: Transition-StateStabilization and the Avoidance of Abortive Reactions
O2- and α-Ketoglutarate-Dependent Tyrosyl Radical Formation in TauD, an α-KetoAcid-Dependent Non-Heme Iron Dioxygenase
Dynamics of Protein and Chromophore Structural Changes in the Photocycle ofPhotoactive Yellow Protein Monitored by Time-Resolved Optical RotatoryDispersion,
Generation of an Active Monomer of Rabbit Muscle Creatine Kinase bySite-Directed Mutagenesis: The Effect of Quaternary Structure on Catalysisand Stability
(4-Hydroxyphenyl)pyruvate Dioxygenase from Streptomyces avermitilis: The Basisfor Ordered Substrate Addition
Effect of pH on the Iso-1-cytochrome c Denatured State: Changing Constraints Dueto Heme Ligation
Reaction of 1-Amino-2-methylenecyclopropane-1-carboxylate with1-Aminocyclopropane-1-carboxylate Deaminase: Analysis and MechanisticImplications
Carboxylate Groups on the Manganese-Stabilizing Protein Are Required forEfficient Binding of the 24 kDa Extrinsic Protein to Photosystem II
Entropic Nature of the Interaction between Promoter Bound CRP Mutants and RNAPolymerase
The Interaction of DOF Transcription Factors with Nucleosomes Depends on thePositioning of the Binding Site and Is Facilitated by Maize HMGB5
Arginine Vasopressin Inhibition of Cyclin D1 Gene Expression Blocks the CellCycle and Cell Proliferation in the Mouse Y1 Adrenocortical Tumor Cell Line
Concerning the Chemical Nature of Tubulin Subunits That Cap and StabilizeMicrotubules
Characterization of Metal Ligand Mutants of Tyrosine Hydroxylase: Insights intothe Plasticity of a 2-Histidine-1-Carboxylate Triad
Zinc- and pH-Dependent Conformational Transition in a Putative InterdomainLinker Region of the Influenza Virus Matrix Protein M1
Characterization of a Mutant Bacillus subtilis Adenylosuccinate Lyase Equivalent toa Mutant Enzyme Found in Human Adenylosuccinate Lyase Deficiency: Asparagine 276 Plays an Important Structural Role
Structure of Tetrahydrobiopterin Tunes its Electron Transfer to the Heme−DioxyIntermediate in Nitric Oxide Synthase
Slow Binding of Retinal to Rhodopsin Mutants G90D and T94D
Solution Structure and DNA Binding Property of the Fifth HMG Box Domain inComparison with the First HMG Box Domain in Human Upstream BindingFactor,
Multiple Metalloproteinases Process Protransforming Growth Factor-α (ProTGF-α)
Role of Hydrophobic Interactions in the Flavodoxin Mediated Electron Transferfrom Photosystem I to Ferredoxin-NADP+ Reductase in Anabaena PCC 7119
The Catalytic Power of Ketosteroid Isomerase Investigatedby Computer Simulation
Oxygen and Hydrogen Isotope Effects in an Active Site Tyrosine to PhenylalanineMutant of Peptidylglycine α-Hydroxylating Monooxygenase: MechanisticImplications
Dynamic Properties of the G93A Mutant of Copper−Zinc Superoxide Dismutase AsDetected by NMR Spectroscopy: Implications for the Pathology of FamilialAmyotrophic Lateral Sclerosis
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