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De Novo Design of a Copper(II)-Binding Helix−Turn−Helix Chimera: The PrionOctarepeat Motif in a New Context
Fluorous Effect in Proteins: De Novo Design and Characterization of aFour-α-Helix Bundle Protein Containing Hexafluoroleucine
Disruption of the LOV−Jα Helix Interaction Activates Phototropin Kinase Activity
Mechanistic Studies of the Oxidation of Oxyhemoglobin by Peroxynitrite
Binding of Antitumor Antibiotic Daunomycin to Histones in Chromatin and inSolution
Crystal Structures of Escherichia coli RecA in Complex with MgADP andMnAMP−PNP,
Enhancing the Activity of Insulin at the Receptor Interface: Crystal Structure andPhoto-Cross-Linking of A8 Analogues
Purification and Structural Characterization of Transforming Growth Factor BetaInduced Protein (TGFBIp) from Porcine and Human Corneas
Solution Structure and Stability against Digestion of rproBnIb, a Recombinant 2SAlbumin from Rapeseed: Relationship to Its Allergenic Properties,
Binding of Oxidized and Reduced Cytochrome c2 to Photosynthetic ReactionCenters: Plasmon-Waveguide Resonance Spectroscopy
GRP1 Pleckstrin Homology Domain: Activation Parameters and Novel SearchMechanism for Rare Target Lipid
Conformational Changes in the Active Site Loops of Dihydrofolate Reductaseduring the Catalytic Cycle
Carotenoid-Induced Cooperative Formation of Bacterial PhotosyntheticLH1 Complex
Single-Stranded Adenine-Rich DNA and RNA Retain Structural Characteristics ofTheir Respective Double-Stranded Conformations and Show Directional Differencesin Stacking Pattern
The Variable C-Terminus of Cysteine String Proteins Modulates Exocytosis andProtein−Protein Interactions
Yeast Frataxin Solution Structure, Iron Binding, and Ferrochelatase Interaction,
Caveolin-1 Functions as a Scaffolding Protein for Phosphofructokinase in theMetabolic Organization of Vascular Smooth Muscle
Phosphoregulation of Mixed-Lineage Kinase 1 Activity by Multiple Phosphorylationin the Activation Loop
Streptococcus pneumoniae Isoprenoid Biosynthesis Is Downregulated byDiphosphomevalonate: An Antimicrobial Target
Evidence for a Substrate Specific and Inhibitable Drug Efflux System inChloroquine Resistant Plasmodium falciparum Strains
Impact of the Acidic C-Terminal Region Comprising Amino Acids 109−140 onα-Synuclein Aggregation in Vitro
The Isoform-Specific Region of the Na,K-ATPase Catalytic Subunit: Role inEnzyme Kinetics and Regulation by Protein Kinase C
Biosynthesis of Colitose: Expression, Purification, and Mechanistic Characterizationof GDP-4-keto-6-deoxy-d-mannose-3-Dehydrase (ColD) and GDP-l-colitoseSynthase (ColC)
Solution Structure of Human β-Parvalbumin and Structural Comparison with ItsParalog α-Parvalbumin and with Their Rat Orthologs,
Protein Kinase CK1δ Phosphorylates Key Sites in the Acidic Domain of MurineDouble-Minute Clone 2 Protein (MDM2) That Regulate p53 Turnover
Solution Structure, Backbone Dynamics, and Association Behavior of theC-Terminal BRCT Domain from the Breast Cancer-Associated Protein BRCA1,
A General Framework for Development and Data Analysis of CompetitiveHigh-Throughput Screens for Small-Molecule Inhibitors of Protein−ProteinInteractions by Fluorescence Polarization
Identification of Membrane-Anchoring Domains of RLIP76 Using Deletion MutantAnalyses
Characterization of the High-Spin Heme x in the Cytochrome b6f Complex ofOxygenic Photosynthesis
Substrate Discrimination by Formamidopyrimidine-DNA Glycosylase: Distinguishing Interactions within the Active Site
Toward the Insulin−IGF-I Intermediate Structures: Functional and StructuralProperties of the [TyrB25NMePheB26] Insulin Mutant
Biochemical Analysis of the Substrate Specificity of the β-Ketoacyl-Acyl CarrierProtein Synthase Domain of Module 2 of the Erythromycin Polyketide Synthase
Mechanism of the Dihydroorotase Reaction
Evaluation of the DNA Binding Tendencies of the Transition State Regulator AbrB
Retention of Conformational Flexibility in HIV-1 Rev−RNA Complexes
NMR Structure of Transcription Factor Sp1 DNA Binding Domain,
Solid-State NMR Analysis of Ligand−Receptor Interactions Reveals an InducedMisfit in the Binding Site of Isorhodopsin
The Membrane-Associated Lipoprotein-9 GmpC from Staphylococcus aureus Bindsthe Dipeptide GlyMet via Side Chain Interactions,
Analysis of Non-Template-Directed Nucleotide Addition and Template Switchingby DNA Polymerase
Ionic Mobilities of Duplex and Frayed Wire DNA in Discontinuous BufferElectrophoresis: Evidence of Interactions with Amino Acids
Preparation and X-ray Structures of Metal-Free, Dicobalt and Dimanganese Formsof Soluble Methane Monooxygenase Hydroxylase from Methylococcus capsulatus(Bath)
Functional Analysis of Acidic Amino Acids in the Cytosolic Tail of the Na+/H+Exchanger
Efficient Silencing of bcr/abl Oncogene by Single- and Double-Stranded siRNAsTargeted against b2a2 Transcripts
Kinetic Stability of Cu/Zn Superoxide Dismutase Is Dependent on Its MetalLigands: Implications for ALS
α-Conotoxins ImI and ImII Target Distinct Regions of the Human α7 NicotinicAcetylcholine Receptor and Distinguish Human Nicotinic Receptor Subtypes
Interaction of Nitric Oxide with Cytochrome P450 BM3
Further Investigation on the Turnover of Escherichia coli Biotin Synthase withDethiobiotin and 9-Mercaptodethiobiotin as Substrates
Stability of DNA Duplexes with Watson−Crick Base Pairs: A Predicted Model
Discovery of Small-Molecule Inhibitors of the NFAT−Calcineurin Interaction byCompetitive High-Throughput Fluorescence Polarization Screening
Ca2+ Activation of the cPLA2 C2 Domain: Ordered Binding of Two Ca2+ Ions withPositive Cooperativity
Harmane and Harmalan Are Bioactive Components of ClassicalClonidine-Displacing Substance
Biophysical Characterization of Human XRCC1 and Its Binding to Damaged andUndamaged DNA
Insights into Redox Partner Interactions and Substrate Binding in Nitrite Reductasefrom Alcaligenes xylosoxidans: Crystal Structures of the Trp138His andHis313Gln Mutants,
Selection of Stable RNA Molecules that Can Regulate the Channel-OpeningEquilibrium of the Membrane-Bound γ-Aminobutyric Acid Receptor
Monoubiquitinated Histone H1B Is Required for Antiviral Protection in CD4+TCells Resistant to HIV-1
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