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Copyright © 2005 American Chemical Society
Copyright © 2005 by the American Chemical Society
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Diversity of Function in the Isocitrate Lyase Enzyme Superfamily: The Dianthuscaryophyllus Petal Death Protein Cleaves α-Keto and α-Hydroxycarboxylic Acids
Kinetic and Chemical Mechanisms of the fabG-Encoded Streptococcus pneumoniaeβ-Ketoacyl-ACP Reductase
Experimental Validation of the Docking Orientation of Cdc25 with Its Cdk2−CycAProtein Substrate
Crystal Structure of the Petal Death Protein from Carnation Flower,
Guanidine Derivatives Rescue the Arg418Ala Mutation of Tritrichomonas foetusIMP Dehydrogenase
Role of the N-Terminal Extension of the (βα)8-Barrel Enzyme Indole-3-glycerolPhosphate Synthase for Its Fold, Stability, and Catalytic Activity,
Kernel Energy Method: Application to DNA
Structural Conservation of Mouse and Rat Zona Pellucida Glycoproteins. Probingthe Native Rat Zona Pellucida Proteome by Mass Spectrometry
Characterization of Autocatalytic Conversion of Precursor BACE1 by HeteronuclearNMR Spectroscopy
Assembly of Tubulin by Classic Myelin Basic Protein Isoforms and Regulation byPost-Translational Modification
A Bivalent Dissectional Analysis of the High-Affinity Interactions between Cdc42and the Cdc42/Rac Interactive Binding Domains of Signaling Kinases in Candidaalbicans
Computational Studies of the Farnesyltransferase Ternary Complex Part I: SubstrateBinding
The Saccharomyces cerevisiae Linker Histone Hho1p, with Two Globular Domains,Can Simultaneously Bind to Two Four-Way Junction DNA Molecules
Definable Equilibrium States in the Folding of Human Prion Protein
Potential of Mean Force Calculation for the Proton and Hydride Transfer ReactionsCatalyzed by Medium-Chain Acyl-CoA Dehydrogenase: Effect of Mutations onEnzyme Catalysis
Probing Heme Propionate Involvement in Transmembrane Proton Transfer Coupledto Electron Transfer in Dihemic Quinol:Fumarate Reductase by 13C-Labeling andFTIR Difference Spectroscopy
Analysis of Interactions with Mitochondrial mRNA Using Mutant Forms of YeastNAD+-Specific Isocitrate Dehydrogenase
Thermodynamics of RNA Duplexes with Tandem Mismatches Containing aUracil-Uracil Pair Flanked by C·G/G·C or G·C/A·U Closing Base Pairs
Independent Heterologous Fibrillation of Insulin and Its B-Chain Peptide
Prevention of MKK6-Dependent Activation by Binding to p38α MAP Kinase
Structural Rationale for Low-Nanomolar Binding of Transition State Mimics to aFamily GH3 β-d-Glucan Glucohydrolase from Barley,
Calcium- and Membrane-Induced Changes in the Structure and Dynamics of ThreeHelical Hairpins in Annexin B12
Sanguinarine Blocks Cytokinesis in Bacteria by Inhibiting FtsZ Assembly andBundling
The Active Site Cysteine of Ubiquitin-Conjugating Enzymes Has a SignificantlyElevated pKa: Functional Implications
Tetraplex DNA Transitions within the Human c-myc Promoter Detected byMultivariate Curve Resolution of Fluorescence Resonance Energy Transfer
Role of Q52 in Catalysis of Decarboxylation and Transamination in DialkylglycineDecarboxylase
ATPase Mechanism of Eg5 in the Absence of Microtubules: Insight intoMicrotubule Activation and Allosteric Inhibition by Monastrol
Disulfide Structure of the Leucine-Rich Repeat C-Terminal Cap and C-TerminalStalk Region of Nogo-66 Receptor
A Slow, Tight-Binding Inhibitor of the Zinc-Dependent Deacetylase LpxC of LipidA Biosynthesis with Antibiotic Activity Comparable to Ciprofloxacin
The Reaction of LipB, the Octanoyl-[Acyl Carrier Protein]:ProteinN-Octanoyltransferase of Lipoic Acid Synthesis, Proceeds through an Acyl-EnzymeIntermediate
An Elementary Reaction Step of the Proton Pump Is Revealed by Mutation ofTryptophan-164 to Phenylalanine in Cytochrome c Oxidase from Paracoccusdenitrificans
Spectroscopic and Biochemical Characterization of Heme Binding to Yeast Dap1pand Mouse PGRMC1p
Structural Analysis of Silanediols as Transition-State-Analogue Inhibitors of theBenchmark Metalloprotease Thermolysin,
Implications of Surface Charge and Curvature for the Binding Orientation ofThermomyces lanuginosus Lipase on Negatively Charged or ZwitterionicPhospholipid Vesicles As Studied by ESR Spectroscopy
Structural Dynamics of the α-Neurotoxin−Acetylcholine-Binding Protein Complex: Hydrodynamic and Fluorescence Anisotropy Decay Analyses
Förster Resonance Energy Transfer Measurements Are Consistent with a HelicalBundle Model for Lipid-Free Apolipoprotein A-I
Partitioning Conformational Intermediates between Competing Refolding andAggregation Pathways: Insights into Transthyretin Amyloid Disease
Conformational Changes of Yeast Plasma Membrane H+-ATPase during Activationby Glucose: Role of Threonine-912 in the Carboxy-Terminal Tail
Shotgun Lipidomics Identifies Cardiolipin Depletion in Diabetic MyocardiumLinking Altered Substrate Utilization with Mitochondrial Dysfunction
Determinants in tRNA for Activation of Arginyl-tRNA Synthetase: Evidence thattRNA Flexibility Is Required for the Induced-Fit Mechanism
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