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2D NMR Study of the DNA Duplexd(CTCTC*A*ACTTCC)·d(GGAAGTTGAGAG) Cross-Linked by theAntitumor-Active Dirhodium(II,II) Unit at the Cytosine−Adenine Step
Revisiting Heme Mechanisms. A Perspective on the Mechanisms of Nitric OxideSynthase (NOS), Heme Oxygenase (HO), and Cytochrome P450s (CYP450s)
Characterization of the Thioether Product Formed from the Thiolytic Cleavage ofthe Alkyl−Nickel Bond in Methyl-Coenzyme M Reductase
Analysis of Flavin Oxidation and Electron-Transfer Inhibition in Plasmodiumfalciparum Dihydroorotate Dehydrogenase
Solution Structure of a Double Mutant of the Carboxy-Terminal DimerizationDomain of the HIV-1 Capsid Protein,
Raman Optical Activity and Circular Dichroism Reveal Dramatic Differences in theInfluence of Divalent Copper and Manganese Ions on Prion Protein Folding
Altered Thermodynamics from Remote Mutations Altering Human toward BovinePurine Nucleoside Phosphorylase
Molecular Engineering of Myoglobin: Influence of Residue68 on the Rate and the Enantioselectivity of OxidationReactions Catalyzed by H64D/V68X Myoglobin,
Evidence for the Involvement of Acid/Base Chemistry in the Reaction Catalyzed bythe Type II Isopentenyl Diphosphate/Dimethylallyl Diphosphate Isomerase fromStaphylococcus aureus
Melatonin Is a Potent Inhibitor for Myeloperoxidase
Characterization of Metal Binding in the Active Sites of Acireductone DioxygenaseIsoforms from Klebsiella ATCC 8724
Impact of the Oxidized Guanine Lesion Spiroiminodihydantoin on the Conformationand Thermodynamic Stability of a 15-mer DNA Duplex
Pea Seed Lectin Folds and Oligomerizes via an Intermediate Not Represented in theStructural Hierarchy
Substrate Recognition Mechanism of the Peptidase Domain of theQuorum-Sensing-Signal−Producing ABC Transporter ComA from Streptococcus
Proper Positioning of the Nicotinamide Ring Is Crucial for theAscaris suum Malic Enzyme Reaction
Critical Role of Specific Ions for Ligand-Induced Changes Regulating PyruvateDehydrogenase Kinase Isoform 2
Characterization of SiaA, a Streptococcal Heme-Binding Protein Associated with aHeme ABC Transport System
Transthyretin Interacts with Metallothionein 2
StAR-like Activity and Molten Globule Behavior of StARD6, A Male Germ-LineProtein
DFT Analysis of Axial and Equatorial Effects on Heme−CO Vibrational Modes: Applications to CooA and H−NOX Heme Sensor Proteins
Modulation of E-Cadherin Monomer Folding by Cooperative Binding of CalciumIons
The Molecular Composition of Square Arrays
Conformational Change Induced by ATP Binding in the Multidrug ATP-BindingCassette Transporter BmrA
P22 c2 Repressor−Operator Complex: Mechanisms of Direct and Indirect Readout
Solid-State NMR Analysis Comparing the Designer-Made Antibiotic MSI-103 withIts Parent Peptide PGLa in Lipid Bilayers
Remote Mutations Alter Transition-State Structure of Human Purine NucleosidePhosphorylase
β-Hematin Interaction with the Hemopexin Domain of Gelatinase B/MMP-9Provokes Autocatalytic Processing of the Propeptide, Thereby Priming Activationby MMP-3
β2-Microglobulin Amyloid Fragment Organization and Morphology andIts Comparison to Aβ Suggests That Amyloid AggregationPathways Are Sequence Specific
Amyloid Nucleation Triggered by Agitation of β2-Microglobulin under Acidic andNeutral pH Conditions
The Kinase Domain Alters the Kinetic Properties of the Myosin IIIA Motor
Is There a Preferential Interaction between Cholesterol and Tryptophan Residues inMembrane Proteins?
Specific Ion Influences on Self-Association of Pyruvate Dehydrogenase KinaseIsoform 2 (PDHK2), Binding of PDHK2 to the L2 Lipoyl Domain, andEffects of the Lipoyl Group-Binding Site Inhibitor, Nov3r
The Kinetic Mechanism of Manganese-Containing Superoxide Dismutase fromDeinococcus radiodurans: A Specialized Enzyme for the Elimination of HighSuperoxide Concentrations
Active Site and Loop 4 Movements within Human Glycolate Oxidase: Implicationsfor Substrate Specificity and Drug Design
NMR Structure of DREAM: Implications for Ca2+-Dependent DNA Binding andProtein Dimerization,
Nucleation, Growth, and Activation Energies for Seeded and Unseeded Aggregationof α-Chymotrypsinogen A
Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent ofIntermolecular Ring Heterodimers,
Proton Transfer in Carbonic Anhydrase Is Controlled by Electrostatics Rather thanthe Orientation of the Acceptor
Is Cytochrome b Glutamic Acid 272 a Quinol Binding Residue in the bc1 Complexof Saccharomyces cerevisiae?
Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPVIon Channels,
Second-Sphere Amino Acids Contribute to Transition-State Structure in BovinePurine Nucleoside Phosphorylase
Understanding Functional Divergence in Proteins by Studying IntragenomicHomologues
Mutagenesis of Folylpolyglutamate Synthetase Indicates That Dihydropteroate andTetrahydrofolate Bind to the Same Site
Isomerization of a Single Aspartyl Residue of Anti-Epidermal Growth FactorReceptor Immunoglobulin γ2 Antibody Highlights the Role Avidity Plays inAntibody Activity
Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step,Minimal/“Ockham's Razor” Model: The Finke−Watzky Mechanism of NucleationFollowed by Autocatalytic Surface Growth
Steady-State and Pre-Steady-State Kinetic Evaluation of Severe Acute RespiratorySyndrome Coronavirus (SARS-CoV) 3CLpro Cysteine Protease: Development of anIon-Pair Model for Catalysis
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