| Abstract
| - The synthesis, complexation, and photophysical properties of the Eu(III)-based quinoline cyclenconjugate complex Eu1 and its permanent, noncovalent incorporation into hydrogels as sensitive,interference-free pH sensing materials for biological media are described. The Eu(III) emission in bothsolution and hydrogel media was switched reversibly “on−off” as a function of pH with a large, greaterthan order of magnitude enhancement in Eu(III) emission. The irreversible incorporation of Eu1 intowater-permeable hydrogels was achieved using poly[methyl methacrylate-co-2-hydroxyethyl methacrylate]-based hydrogels, and the luminescent properties of the novel sensor materials, using confocal laser-scanning microscopy and steady state luminescence, were characterized and demonstrated to be retainedwith respect to solution behavior. Water uptake and dehydration behavior of the sensor-incorporatedmaterials was also characterized and shown to be dependent on the material composition.
- Hydrogel matrixes irreversibly bind a sensitive Eu(III)-based quinoline cyclen sensor which can be switched “on” (A) or “off” (B) for interference-free analysis of biological media. Photophysical behavior of the sensor as characterized in aqueous solution is retained in the novel materials.
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