| Abstract
| - The synthesis and chemical properties of a variety of chemically modified calix[4]pyrroles aredescribed. The effects of structural changes, specifically the presence and absence of substituentson the meso-like and β-pyrrolic carbons, on anion affinities are detailed as is their effect onmacrocycle conformation. Also described are unsymmetrical systems, bearing an aliphatic andaromatic substituent on each of the four meso-like carbon atoms. In this case, the properties ofthe resulting configuration isomers are discussed in terms, again, of the resulting effects onmacrocycle conformation and substrate binding affinity. Finally, the use of appropriatelyfunctionalized calix[4]pyrrole systems as rudimentary fluorescence-based anion sensors ispresented.
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