About: Breaking the Degeneracy of the Genetic Code

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Attributs	Valeurs
type	work Article
Is Part Of	http://hub.abes.fr/acs/periodical/jacsat/2003/volume_125/issue_25/w
Subject	Communication
Title	Breaking the Degeneracy of the Genetic Code
has manifestation of work	http://hub.abes.fr/acs/periodical/jacsat/2003/volume_125/issue_25/101021ja0350076/m/print http://hub.abes.fr/acs/periodical/jacsat/2003/volume_125/issue_25/101021ja0350076/m/web
related by	http://hub.abes.fr/acs/periodical/jacsat/2003/volume_125/issue_25/101021ja0350076/authorship/1 http://hub.abes.fr/acs/periodical/jacsat/2003/volume_125/issue_25/101021ja0350076/authorship/3 http://hub.abes.fr/acs/periodical/jacsat/2003/volume_125/issue_25/101021ja0350076/authorship/2
Author	Kwon Inchan Kirshenbaum Kent Tirrell David A.
Abstract	A mutant yeast phenylalanine transfer RNA (ytRNAPheAAA) containing a modified (AAA) anticodon was generated to explore the feasibility of breaking the degeneracy of the genetic code in Escherichia coli. By using an E. coli strain co-transformed with ytRNAPheAAA and a mutant yeast phenylalanyl-tRNA synthetase, we demonstrate efficient replacement of phenylalanine (Phe) by L-3-(2-naphthyl)alanine (Nal) at UUU, but not at UUC codons.
article type	rapid-communication
is part of this journal	Journal of the American Chemical Society

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