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À propos de : 3‘-Ferrocene-Labeled Oligonucleotide Chains End-Tethered to Gold ElectrodeSurfaces: Novel Model Systems for Exploring Flexibility of Short DNA UsingCyclic Voltammetry        

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  • 3‘-Ferrocene-Labeled Oligonucleotide Chains End-Tethered to Gold ElectrodeSurfaces: Novel Model Systems for Exploring Flexibility of Short DNA UsingCyclic Voltammetry
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  • The flexibility of DNA is of central importance in biology, medicine, materials science, and mechanical engineering. In this study, we report an unprecedented electrochemical approach for investigating the flexibility of a short (typically 20-base), surface end-tethered single-stranded synthetic DNA oligonucleotide and of its postformed DNA duplex, taking as an example the homopolymer (dT)20 sequence in the regime of very high ionic strength (∼1 M).
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