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À propos de : Nitrilotriacetic Acid-Modified Magnetic Nanoparticles as a General Agent toBind Histidine-Tagged Proteins        

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  • Nitrilotriacetic Acid-Modified Magnetic Nanoparticles as a General Agent toBind Histidine-Tagged Proteins
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  • Using Nα,Nα-bis(carboxymethyl)lysine to react with FePt magnetic nanoparticles, we synthesized the FePt−NTA conjugate, which immobilizes Ni2+ ions and selectively binds to histidine-tagged proteins at concentration as low as 0.5 pM. This simple system serves as a useful alternative to existing protocols for protein separation and also acts as a versatile agent for transporting and anchoring proteins.
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