About: A PNA4 Quadruplex

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Attributs	Valeurs
type	work Article
Is Part Of	http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_19/w
Subject	Communication
Title	A PNA4 Quadruplex
has manifestation of work	http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_19/101021ja031508f/m/print http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_19/101021ja031508f/m/web
related by	http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_19/101021ja031508f/authorship/1 http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_19/101021ja031508f/authorship/3 http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_19/101021ja031508f/authorship/2
Author	Balasubramanian Shankar Stephens Elaine Krishnan-Ghosh Yamuna
Abstract	A tetrameric PNA, TGGG, has been shown to form an intermolecular G-quadruplex. Nanoelectrospray mass spectrometry, combined with solution-phase H/D exchange, established formation of a specific tetramolecular complex. UV melting studies show that this complex undergoes a quadruplex melting transition. This is a novel four-stranded structure that offers the gross structural features of a DNA quadruplex, but without the negatively charged backbone.
article type	rapid-communication
is part of this journal	Journal of the American Chemical Society

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