About: Modified DNA Analogues That Sense Light Exposure with Color Changes

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Attributs	Valeurs
type	work Article
Is Part Of	http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_40/w
Subject	Communication
Title	Modified DNA Analogues That Sense Light Exposure with Color Changes
has manifestation of work	http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_40/101021ja046910o/m/print http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_40/101021ja046910o/m/web
related by	http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_40/101021ja046910o/authorship/2 http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_40/101021ja046910o/authorship/1 http://hub.abes.fr/acs/periodical/jacsat/2004/volume_126/issue_40/101021ja046910o/authorship/3
Author	Watanabe Soichiro Kool Eric T. Gao Jianmin
Abstract	We report the discovery of a new class of light-sensing molecules. These light sensors are composed of fluorophore oligomers assembled on a DNA backbone. A combinatorial library of tetrafluorophores consisting of over 14 000 compounds was synthesized and screened for rapid responses toward light exposure. Among the most light-sensitive molecules, at least three tetramers were found to respond to light exposure with apparent color changes, rather than simple photobleaching.
article type	rapid-communication
is part of this journal	Journal of the American Chemical Society

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