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À propos de : Domino Coupling Relay Approach to Polycyclic Pyrrole-2-carboxylates        

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  • Domino Coupling Relay Approach to Polycyclic Pyrrole-2-carboxylates
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  • CuBr2-catalyzed three-component coupling of N-benzylallylamine, ethyl glyoxalate, and terminal alkynes afforded glycine-tethered 1,6-enynes, which were further transformed into polycyclic pyrrole-2-carboxylates via novel cycloisomerization/Diels−Alder cycloaddition/dehydrogenation sequence under iridium-catalyzed conditions.
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