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À propos de : Highly Enantioseletive Biginelli Reaction Using a New Chiral YtterbiumCatalyst: Asymmetric Synthesis of Dihydropyrimidines        

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  • Highly Enantioseletive Biginelli Reaction Using a New Chiral YtterbiumCatalyst: Asymmetric Synthesis of Dihydropyrimidines
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  • The highly enantioselective three-component Biginelli condensation catalyzed by a recyclable chiral ytterbium triflate with a novel hexadentate amine phenol ligand containing a pyridyl group has been developed. A wide range of optically active dihydropyrimidines with remarkable pharmacological interest was obtained in high yields with good to excellent enantioselectivities under mild conditions.
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