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À propos de : Multicomponent Domino Reaction from β-Ketoamides: Highly EfficientAccess to Original Polyfunctionalized 2,6-Diazabicyclo[2.2.2]octane Cores        

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  • Multicomponent Domino Reaction from β-Ketoamides: Highly EfficientAccess to Original Polyfunctionalized 2,6-Diazabicyclo[2.2.2]octane Cores
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  • We describe a new multicomponent domino reaction from β-ketoamides, involved as substrates and as nucleophilic partners. We obtain highly functionalized and original 2,6-diazabicyclo[2.2.2]octane cores (2,6-DABCO) in a five-step one-pot sequence, which is fast, environmentally friendly, operationally simple to manage, and combines step- and atom-economic aspects.
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