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À propos de : Highly Efficient Au(I)-Catalyzed Intramolecular Addition of β-Ketoamide toUnactivated Alkenes        

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  • Highly Efficient Au(I)-Catalyzed Intramolecular Addition of β-Ketoamide toUnactivated Alkenes
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  • N-Alkenyl β-ketoamides undergo cyclization in the presence of Au[P(t-Bu)2(o-biphenyl)]Cl (5 mol %) and AgOTf (5 mol %) under mild conditions with excellent regioselectivities and yields. The reaction provides an efficient method to prepare highly substituted lactams.
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