Abstract
| - We report on the oligosaccharide recognition through noncovalent interactions in water basedon a unique supramolecular homoduplex-to-heteroduplex transformation of the oligoresorcinol nonameras a fully artificial receptor. The oligoresorcinol forms a double helix in water, which unravels and entwinesupon complexation with specific oligosaccharides with a particular chain length and glucosidic linkage pattern,thus generating the heteroduplex with an excess one-handed helical conformation that can be readilymonitored and further quantified by absorption, circular dichroism, and NMR spectroscopies.
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