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Title
| - Electrical Behavior of Droplet Interface Bilayer Networks: Experimental Analysis and Modeling
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Abstract
| - Aqueous droplets submerged in an oil−lipid mixture become enclosed by a lipid monolayer.The droplets can be connected to form robust networks of droplet interface bilayers (DIBs) with functionssuch as a biobattery and a light sensor. Such DIB networks might be used as model systems for the studyof membrane-based biological phenomena. In this study, we develop and experimentally validate an electricalmodeling approach for DIB networks by applying it to describe the current flow through a simple networkcontaining protein pores and blocking molecules. We demonstrate the use of SPICE (Simulation Programwith Integrated Circuit Emphasis) for simulating the electrical behavior of DIB networks. The modular andscalable nature of DIB networks should enable a straightforward extension of the analysis presented inthis paper to large, complex networks.
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