| Abstract
| - Organosulfur compounds and sodium bisulfite significantly inhibited (P< 0.05) heterocyclic aromaticamine (HAA) formation in model systems containing phenylalanine, creatinine, and glucose. Therewas, however, no inhibition by the same compounds in a model system containing only phenylalanineand creatinine. Diallyl disulfide (DAD) and dipropyl disulfide (DPD) concentrations in the model systemswere significantly decreased (P< 0.05) after heating for 10 min at 180 °C. Only very low concentrationsof sulfhydryl groups (4.19 and 4.00 μmol) were produced on heating DAD and DPD for 30 min.Reaction of glucose and DAD produced several sulfur-containing compounds. After 10 min of heatingat 180 °C, HAA formation in the control model systems was increased significantly, and DAD was aneffective inhibitor during this heating period. Tetrahydrothiophene-3-one (THT) and tetrahydrothiophene(THP); two products resulting from the interaction of glucose and DAD, had no direct influence onHAA formation in the model systems. Keywords: Heterocyclic aromatic amine; sulfur compound; model system; tetrahydrothiophene-3-one; tetrahydrothiophene
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