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http://hub.abes.fr/acs/periodical/jmcmar/1989/volume_32/issue_11/101021jm00131a009/m/web
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10.1021/jm00131a009
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Structural studies on bioactive compounds. 8. Synthesis, crystal structure and biological properties of a new series of 2,4-diamino-5-aryl-6-ethylpyrimidine dihydrofolate reductase inhibitors with in vivo activity against a methotrexate-resistant tumor cell line
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