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Selective and enantiospecific acylation of .kappa.-opioid receptors by (1S,2S)-trans-2-isothiocyanato-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide. Demonstration of .kappa. receptor heterogeneity
Cyclic enkephalin analog containing .alpha.-amino-.beta.-mercapto-.beta.,.beta.-pentamethylenepropionic acid at position 2 or 5
Bifunctional antitumor compounds. Interaction of adriamycin with metallocene dichlorides
Solid-phase synthesis of 16 potent (selective and nonselective) in vivo antagonists of oxytocin
Synthesis and structure-activity studies of some disubstituted phenylisoxazoles against human picornavirus
Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluaton of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimidazolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases
Potent angiotensin II antagonists with non-.beta.-branched amino acids in position 5
Carbamyl analogs of potent, nicotinic agonists: pharmacology and computer-assisted molecular modeling study
Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides
Synthesis, cytotoxicity, and antiviral activity of some acyclic analogs of the pyrrolo[2,3-d]pyrimidine nucleoside antibiotics tubercidin, toyocamycin, and sangivamycin
Studies on hindered phenols and analogs. 1. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation
Synthesis and copper-dependent antimycoplasmal activity of 1-amino-3-(2-pyridyl)isoquinoline derivatives. 2. Amidines
Syntheses and biological activities of 13-substituted avermectin aglycons
Conformationally defined adrenergic agents. 15. Conformationally restricted and conformationally defined tyramine analogs as inhibitors of phenylethanolamine N-methyltransferase
Studies on angiotensin converting enzyme inhibitors. 4. Synthesis and angiotensin converting enzyme inhibitory activities of 3-acyl-1-alkyl-2-oxoimidazolidine-4-carboxylic acid derivatives
A novel class of "GABAergic" agents: 1-aryl-3-(aminoalkylidene)oxindoles
Synthesis and cytostatic activity of geiparvarin analogs
Selective thyromimetics. Cardiac-sparing thyroid hormone analogs containing 3'-arylmethyl substituents
Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3(2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for the treatment of congestive heart failure
New brain perfusion imaging agents based on technetium-99m bis(aminoethanethiol) complexes: stereoisomers and biodistribution
Synthesis and evaluation of antileukemic activity of 5-thienyl- or 5-(2-furyl)-2,3-dihydro-6,7-bis(hydroxymethyl)-1H-pyrrolizine bis(alkylcarbamates) and derivatives
Structure-activity relationships of novel vasopressin antagonists containing C-terminal diaminoalkanes and (aminoalkyl)guanidines
Synthesis and biological evaluation of 14-alkoxymorphinans. 2. (-)-N-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one, a selective .mu. opioid receptor antagonist
1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent
Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 3. Synthesis and evaluation of (alkenyloxy)-, (alkynyloxy)-, and (aralykyloxy)methyl quaternarized 2-[(hydroxyimino)methyl]-1-alkylimidazolium halides as reactivators and therapy for soman intoxication
Synthesis and radioprotective activity of dipeptide cysteamine and cystamine derivatives
Deaminoteicoplanin and its derivatives. Synthesis, antibacterial activity, and binding strength to Ac-D-Ala-D-Ala
Full agonists of CCK8 containing a nonhydrolyzable sulfated tyrosine residue
Spermexatin and spermexatol: new synthetic spermidine-based siderophore analogs
A new series of tricyclic (aryloximino)propanolamines displaying very high selective .beta.2-blocking properties
Studies on semirigid tricyclic analogs of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as minimal DNA-intercalating antitumor agents with in vivo solid tumor activity
Studies on bioactive compounds. 13. Synthesis and lack of growth-inhibitory properties of cyclohexane-1,2,4-triol 1,2-diesters, which resemble ring C of the phorbol ester molecule
Cardiotonic agents. 1-Methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and related compounds. Synthesis and activity
Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs
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