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Anilide Derivatives of an 8-Phenylxanthine Carboxylic Congener Are HighlyPotent and Selective Antagonists at Human A2B Adenosine Receptors
Design, Synthesis, and AntimicrobialActivity of 6-O-Substituted KetolidesActive against Resistant RespiratoryTract Pathogens
Artificial Neural Network Applied to Prediction of FluorquinoloneAntibacterial Activity by Topological Methods
SH2-Directed Ligands of the Lck Tyrosine Kinase
Novel and Selective Calcitonin-Inducing Agents
Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. PotentDopamine and Serotonin Reuptake Inhibitors
Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonistsas Water-Soluble Prodrugs
Highly Selective Chiral N-Substituted 3α-[Bis(4‘-fluorophenyl)methoxy]tropaneAnalogues for the Dopamine Transporter: Synthesis and ComparativeMolecular Field Analysis
Conformationally Constrained Butyrophenones with Mixed Dopaminergic (D2) and Serotoninergic (5-HT2A, 5-HT2C) Affinities: Synthesis, Pharmacology, 3D-QSAR, and Molecular Modeling of (Aminoalkyl)benzo- and -thienocycloalkanones as Putative Atypical Antipsychotics.
Design and SAR of Novel Potassium Channel Openers Targeted for UrgeUrinary Incontinence. 1. N-Cyanoguanidine Bioisosteres Possessing in VivoBladder Selectivity
Molecular Modeling of the Aldose Reductase-Inhibitor Complex Based on theX-ray Crystal Structure and Studies with Single-Site-Directed Mutants
Active Conformations of Neotame and Other High-Potency Sweeteners
Pyrrolidine Inhibitors of HumanCytosolic Phospholipase A2
Methyl-Substituted Dispiro-1,2,4,5-tetraoxanes: Correlations of StructuralStudies with Antimalarial Activity
5-HT Reuptake Inhibitors with 5-HT1B/1D Antagonistic Activity: A NewApproach toward Efficient Antidepressants
Design and SAR of Novel Potassium Channel Openers Targeted for UrgeUrinary Incontinence. 2. Selective and Potent Benzylamino Cyclobutenediones
Histaprodifens: Synthesis, Pharmacological in Vitro Evaluation, and MolecularModeling of a New Class of Highly Active and Selective Histamine H1-ReceptorAgonists
1,2,4-Triazolo[4,3-a]quinoxalin-1-one: A Versatile Tool for the Synthesis ofPotent and Selective Adenosine Receptor Antagonists
Doubly Homologated Dihalovinyl and Acetylene Analogues of Adenosine: Synthesis, Interaction with S-Adenosyl-l-homocysteine Hydrolase, and Antiviraland Cytostatic Effects
3D-QSAR CoMFA Study on Imidazolinergic I2 Ligands: A Significant Modelthrough a Combined Exploration of Structural Diversity and Methodology
Investigating Protein−Ligand Interactions with a Mutant FKBP Possessing aDesigned Specificity Pocket
Mapping the Melatonin Receptor. 6. Melatonin Agonists and AntagonistsDerived from 6H-Isoindolo[2,1-a]indoles, 5,6-Dihydroindolo[2,1-a]isoquinolines,and 6,7-Dihydro-5H-benzo[c]azepino[2,1-a]indoles
2‘,6‘-Dimethylphenoxyacetyl: A New Achiral High Affinity P3-P2 Ligand forPeptidomimetic-Based HIV Protease Inhibitors
Biarylcarbamoylindolines Are Novel and Selective 5-HT2C Receptor InverseAgonists: Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a PotentialAntidepressant/Anxiolytic Agent
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