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2001
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Copyright © 2001 American Chemical Society
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23
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Synthesis and Biological Evaluation of Tropane-like1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine (GBR12909) Analogues
Methylene−gem-Difluorocyclopropane Analogues of Nucleosides: Synthesis,Cyclopropene−Methylenecyclopropane Rearrangement, and Biological Activity
Structure−Affinity Relationships of a Unique Nicotinic Ligand: N-Dimethyl-N4-phenylpiperazinium Iodide (DMPP)
New Pyridoquinoline Derivatives as Potential Inhibitors of theFluoroquinolone Efflux Pump in Resistant Enterobacter aerogenes Strains
Synthesis and Activity of Novel and Selective IKs-Channel Blockers
Phenoxypropoxybiguanides, Prodrugs of DHFR−Inhibiting DiaminotriazineAntimalarials
Structure−Activity Studies on Nociceptin Analogues: ORL1 Receptor Bindingand Biological Activity of Cyclic Disulfide-Containing Analogues of NociceptinPeptides
Evaluation of Docking Functions for Protein−Ligand Docking
Synthesis and Biological Evaluation of a Novel Series of Furans: LigandsSelective for Estrogen Receptor α
Discovery of a Series of Nonpeptide Small Molecules That Inhibit the Bindingof Insulin-like Growth Factor (IGF) to IGF-Binding Proteins
Design and Synthesis of 4-SubstitutedBenzamides as Potent, Selective, andOrally Bioavailable IKs Blockers
Pseudoproline-Containing Analogues of Morphiceptin and Endomorphin-2:Evidence for a Cis Tyr−Pro Amide Bond in the Bioactive Conformation
Acetylcholinesterase Inhibitors: SAR and Kinetic Studies onω-[N-Methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyarylDerivatives
One-Dimensional Molecular Representations and Similarity Calculations: Methodology and Validation
Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors ofSrc Kinase Activity
N-Arylsulfonylindole Derivatives as Serotonin 5-HT6 Receptor Ligands
Exploiting Subsite S1 of Trypsin-Like Serine Proteases for Selectivity: Potentand Selective Inhibitors of Urokinase-Type Plasminogen Activator
Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 5. Highly Selective,Potent, and Orally Active ETA Antagonists
Design, Synthesis, and Characterization of the Antitumor Activity of NovelCeramide Analogues
Antitumor Agents. 211. Fluorinated 2-Phenyl-4-quinolone Derivatives asAntimitotic Antitumor Agents
Preparation and Evaluation of Sulfide Derivatives of the Antibiotic Brefeldin Aas Potential Prodrug Candidates with Enhanced Aqueous Solubilities
Novel Lead Generation throughHypothetical PharmacophoreThree-Dimensional Database Searching: Discovery of Isoflavonoids asNonsteroidal Inhibitors of Rat5α-Reductase
Synthesis and Screening for Antiacetylcholinesterase Activity of(1-Benzyl-4-oxopiperidin-3-ylidene)methylindoles and -pyrroles Related toDonepezil
Modeling of Poly(ADP-ribose)polymerase (PARP) Inhibitors. Docking ofLigands and Quantitative Structure−Activity Relationship Analysis
Three-Dimensional Quantitative Structure−Activity Relationship (3D-QSAR)Models for a Novel Class of Piperazine-Based Stromelysin-1 (MMP-3)Inhibitors: Applying a “Divide and Conquer” Strategy
Enantiomeric Synthesis of d- and l-Cyclopentenyl Nucleosides and TheirAntiviral Activity Against HIV and West Nile Virus
17α-O-(Aminoalkyl)oxime Derivatives of 3β,14β-Dihydroxy-5β-androstane and3β-Hydroxy-14-oxoseco-D-5β-androstane as Inhibitors of Na+,K+-ATPase at theDigitalis Receptor
Structure−Activity Studies of the Phe4 Residue of Nociceptin(1−13)-NH2: Identification of Highly Potent Agonists of the Nociceptin/Orphanin FQReceptor
Iridals Are a Novel Class of Ligands for Phorbol Ester Receptors with ModestSelectivity for the RasGRP Receptor Subfamily
A Novel Series of 2,6,7-Substituted 2,3-Dihydro-1,4-Benzodioxin and2,6,7-Substituted 1,4-Benzodioxin Derivatives as Lipid Peroxidation Inhibitors.Structure−Activity Relationships for High Inhibition of Human Low-DensityLipoprotein Peroxidation
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