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Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)-[1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of BloodCoagulation Factor Xa
Labeling and Evaluation of N-[11C]Methylated Quinoline-2-carboxamides asPotential Radioligands for Visualization of Peripheral BenzodiazepineReceptors
Structure−Activity Studies of Substituted Quinoxalinones asMultiple-Drug-Resistance Antagonists
AMP Deaminase Inhibitors. 5. Design, Synthesis, and SAR of a Highly PotentInhibitor Series
Improved Scoring of Ligand−Protein Interactions Using OWFEG Free EnergyGrids
Structure−Activity Relationships at Monoamine Transporters and MuscarinicReceptors for N-Substituted-3α-(3‘-chloro-, 4‘-chloro-, and4‘,4‘ ‘-dichloro-substituted-diphenyl)methoxytropanes
Synthesis of New Cyclitol Compounds That Influence the Activity ofPhosphatidylinositol 4-Kinase Isoform, PI4K230
Current and Novel Approaches to the Drug Treatment of Schizophrenia
Novel Glucocorticoid Antedrugs Possessing a 17β-(γ-Lactone) Ring
seco-Cyclothialidines: New Concise Synthesis, Inhibitory Activity towardBacterial and Human DNA Topoisomerases, and Antibacterial Properties
2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substratesof Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosomacruzi: Synthesis and Correlation between Redox Cycling Activities and in VitroCytotoxicity
Crystal Structure of Human Cyclin-Dependent Kinase 2 in Complex with theAdenine-Derived Inhibitor H717
Design, Synthesis, and Evaluation of Novel A2A Adenosine Receptor Agonists
Coumarin and Chromen-4-one Analogues as Tautomerase Inhibitors ofMacrophage Migration Inhibitory Factor: Discovery and X-ray Crystallography
Reduction in Glucose Levels in STZ Diabetic Rats by4-(2,2-Dimethyl-1-oxopropyl)benzoic Acid: A Prodrug Approach forTargeting the Liver
A Conformational and Structure−Activity Relationship Study of Cytotoxic3,5-Bis(arylidene)-4-piperidones and Related N-Acryloyl Analogues
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