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Investigation of Neuraminidase-Substrate Recognition Using MolecularDynamics and Free Energy Calculations
Novel sst4-Selective Somatostatin (SRIF) Agonists. 1. Lead Identification Usinga Betide Scan
Novel sst4-Selective Somatostatin (SRIF) Agonists. 2. Analogues withβ-Methyl-3-(2-naphthyl)alanine Substitutions at Position 8
Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design andSynthesis of New Naphtholactam and Naphthosultam Derivatives
Synthesis and Structure−Activity Relationship of Aminobenzophenones. ANovel Class of p38 MAP Kinase Inhibitors with High Antiinflammatory Activity
Rational Design of an Indolebutanoic Acid Derivative as a Novel AldoseReductase Inhibitor Based on Docking and 3D QSAR Studies ofPhenethylamine Derivatives
Structure-Based Design, Synthesis, and Antimicrobial Activity ofIndazole-Derived SAH/MTA Nucleosidase Inhibitors
2-Arylureidobenzoic Acids: Selective Noncompetitive Antagonists for theHomomeric Kainate Receptor Subtype GluR5
Parallel Solid-Phase Synthesis and Evaluation of Inhibitors of Streptomycescoelicolor Type II Dehydroquinase
Synthesis and Biological Evaluation of Iodinated and Fluorinated9-(2-Hydroxypropyl) and 9-(2-Hydroxyethoxy)methyl Purine NucleosideAnalogues
Improving Structure-Based Virtual Screening by Multivariate Analysis ofScoring Data
Bisintercalating Threading Diacridines: Relationships between DNA Binding,Cytotoxicity, and Cell Cycle Arrest
Generation of Bis-Cationic Heterocyclic Inhibitors of Bacillus subtilis HPrKinase/Phosphatase from a Ditopic Dynamic Combinatorial Library
Enantioselective Responses to aPhosphorothioate Analogue ofLysophosphatidic Acid with LPA3Receptor-Selective Agonist Activity
Design, Synthesis, and Biological Evaluation of IndenoisoquinolineTopoisomerase I Inhibitors Featuring Polyamine Side Chains on the LactamNitrogen
Synthesis, in Vitro Affinity, and Efficacyof a Bis 8-Ethynyl-4H-imidazo[1,5a]-[1,4]benzodiazepine Analogue, the FirstBivalent α5 Subtype Selective BzR/GABAA Antagonist
Novel sst4-Selective Somatostatin (SRIF) Agonists. 4. Three-DimensionalConsensus Structure by NMR
Analyses of Activity for Factor Xa Inhibitors Based on Monte Carlo Simulations
Computer Modeling of Selective Regions in the Active Site of Nitric OxideSynthases: Implication for the Design of Isoform-Selective Inhibitors
Synthesis and Pharmacological Identification of Neutral Histamine H1-ReceptorAntagonists
Constrained Derivatives of Stylostatin 1. 1. Synthesis and Biological Evaluationas Potential Anticancer Agents
Systematic Surface Scan of the MostFavorable Interaction Sites ofMagnesium Ions with Tetracycline
Novel Lavendamycin Analogues as Potent HIV-Reverse TranscriptaseInhibitors: Synthesis and Evaluation of Anti-Reverse Transcriptase Activity ofAmide and Ester Analogues of Lavendamycin
Synthesis and Structure−Activity Relationship of Mannose-BasedPeptidomimetics Selectively Blocking Integrin α4β7 Binding to MucosalAddressin Cell Adhesion Molecule-1
Synthesis and Biological Evaluation of3-(4-Substituted-phenyl)-N-hydroxy-2-propenamides, a New Class of HistoneDeacetylase Inhibitors
Design and Synthesis of Novel Bioactive Peptides and Peptidomimetics
Three-Dimensional Quantitative Structure−Activity Relationship Analyses ofPeptide Substrates of the Mammalian H+/Peptide Cotransporter PEPT1
Shape Signatures: A New Approach to Computer-Aided Ligand- andReceptor-Based Drug Design
Novel sst4-Selective Somatostatin (SRIF) Agonists. 3. Analogues Amenable toRadiolabeling
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