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Synthesis and Structure−Activity Relationships of 4-alkynyloxy PhenylSulfanyl, Sulfinyl, and Sulfonyl Alkyl Hydroxamates as Tumor NecrosisFactor-α Converting Enzyme and Matrix Metalloproteinase Inhibitors
Bioconjugation Protocols. Strategies and Methods. Volume 283 in Methods in Molecular Biol-ogy Edited by Christof M. Niemeyer. HumanaPress, Totowa, NJ. 2004. xi + 330 pp. 16 × 24 cm. ISBN1-588-29-098-0. $125.00.
Novel Azido and Isothiocyanato Analogues of[3-(4-Phenylalkylpiperazin-1-yl)propyl]bis(4-fluorophenyl)amines as PotentialIrreversible Ligands for the Dopamine Transporter
Optimization of Protein Kinase CK2 Inhibitors Derived from4,5,6,7-Tetrabromobenzimidazole
Structure−Activity Relationships in Platelet-Activating Factor. 12. Synthesisand Biological Evaluation of Platelet-Activating Factor Antagonists withAnti-HIV-1 Activity
Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Usinga Cell- and Caspase-based High-Throughput Screening Assay. 1.Structure−Activity Relationships of the 4-Aryl Group
Synthesis of Tropeines and Allosteric Modulation of Ionotropic GlycineReceptors
Identification of a Small MoleculeNonpeptide Active Site β-SecretaseInhibitor That Displays a NontraditionalBinding Mode for Aspartyl Proteases
Tetrasubstituted Imidazole Inhibitors of Cytokine Release: ProbingSubstituents in the N-1 Position
Raptor: Combining Dual-Shell Representation, Induced-Fit Simulation, andHydrophobicity Scoring in Receptor Modeling: Application toward theSimulation of Structurally Diverse Ligand Sets
Arylthioindoles, Potent Inhibitors ofTubulin Polymerization
Design, Synthesis, Physicochemical Properties, and Evaluation of Novel IronChelators with Fluorescent Sensors
Time-Related Differences in the Physical Property Profiles of Oral Drugs
Synthesis and Evaluation ofKeto-Glutamine Analogues as PotentInhibitors of Severe Acute RespiratorySyndrome 3CLpro
The Discovery of Orally Active Triaminotriazine Aniline Amides as Inhibitorsof p38 MAP Kinase
Discovery of Novel Phenolic Antioxidants as Inhibitors of Vascular CellAdhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases
Organic Spectroscopic Analysis By Rosaleen J.Anderson, David J. Bensell, and Paul W. Groundwater.Royal Society of Chemistry, Cambridge, U.K. 2004.vi + 175 pp. 19 × 24.5 cm. ISBN 0-85404-476-0. £14.95.
New COX-2/5-LOX Inhibitors: Apoptosis-Inducing Agents Potentially Useful inProstate Cancer Chemotherapy
Lactams as EP4 Prostanoid ReceptorAgonists. 3. Discovery of N-EthylbenzoicAcid 2-Pyrrolidinones as SubtypeSelective Agents
Computational Medicinal Chemistry for DrugDiscovery Edited by Patrick Bultinck, Hans DeWinter, Wilfried Langenaeker, and Jan P. Tollenaere.Marcel Dekker, New York. 2004. xiv + 794 pp. 18 × 26cm. ISBN 0-8247-4774-7. $195.00.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of a Novel,Peripherally Selective Inhibitor of Catechol-O-methyltransferase
Effects of Indole Fatty Alcohols on the Differentiation of Neural Stem CellDerived Neurospheres
Synthesis and Structure−Activity Relationships of Novel Histamine H1Antagonists: Indolylpiperidinyl Benzoic Acid Derivatives
Deriving Knowledge through Data Mining High-Throughput Screening Data
Monoamine Transporter Binding, Locomotor Activity, and Drug DiscriminationProperties of 3-(4-Substituted-phenyl)tropane-2-carboxylic Acid Methyl EsterIsomers
New Constrained “Molecular Tongs” Designed To Dissociate HIV-1 ProteaseDimer
Discovery of Bicyclic Thymidine Analogues as Selective and High-AffinityInhibitors of Mycobacterium tuberculosis Thymidine Monophosphate Kinase
An In Silico Approach to Discovering Novel Inhibitors of Human Sirtuin Type 2
α2-Adrenoreceptors Profile Modulation. 2. Biphenyline Analogues as Tools forSelective Activation of the α2C-Subtype
CoMFA Study of Piperidine Analogues of Cocaine at the DopamineTransporter: Exploring the Binding Mode of the 3α-Substituent of thePiperidine Ring Using Pharmacophore-Based Flexible Alignment
Potent N-(1,3-Thiazol-2-yl)pyridin-2-amine Vascular Endothelial Growth FactorReceptor Tyrosine Kinase Inhibitors with Excellent Pharmacokinetics and LowAffinity for the hERG Ion Channel
A 3D Similarity Method for Scaffold Hopping from Known Drugs or NaturalLigands to New Chemotypes
Novel Bicyclic Piperazine Derivatives of Triazolotriazine andTriazolopyrimidines as Highly Potent and Selective Adenosine A2A ReceptorAntagonists
Broad-Based Quantitative Structure−Activity Relationship Modeling of Potencyand Selectivity of Farnesyltransferase Inhibitors Using a Bayesian RegularizedNeural Network
Acetylcholinesterase Inhibitory Activity of Scopolin and Scopoletin Discoveredby Virtual Screening of Natural Products
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