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Attributs	Valeurs
type	work Issue
Is Part Of	http://hub.abes.fr/acs/periodical/jmcmar/2006/volume_49
has manifestation of work	http://hub.abes.fr/acs/periodical/jmcmar/2006/volume_49/issue_12/m/print http://hub.abes.fr/acs/periodical/jmcmar/2006/volume_49/issue_12/m/web
Date Copyrighted	2006
Rights	Copyright © 2006 American Chemical Society
issue	12
Rights Holder	American Chemical Society
is Is Part Of of	Application of a Mathematical Topological Pattern of Antihistaminic Activity for the Selectionof New Drug Candidates and Pharmacology Assays Potent Antitumor 9-Anilinoacridines and Acridines Bearing an Alkylating N-Mustard Residueon the Acridine Chromophore: Synthesis and Biological Activity Computational Prediction of Oral Drug Absorption Based on Absorption Rate Constants inHumans Synthesis, Structural Reassignment, and Biological Activity of Type B MAO Inhibitors Basedon the 5H-Indeno[1,2-c]pyridazin-5-one Core The Combi-Targeting Concept: Synthesis of Stable Nitrosoureas Designed to Inhibit theEpidermal Growth Factor Receptor (EGFR) The Discovery of New 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors by CommonFeature Pharmacophore Modeling and Virtual Screening Human PEPT1 Pharmacophore Distinguishes between Dipeptide Transport and Binding Discovery, Structure−Activity Relationship, and Pharmacological Evaluation of(5-Substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as Potent Dipeptidyl Peptidase IVInhibitors (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: A Selective α-Amino Amide Dipeptidyl Peptidase IV Inhibitorfor the Treatment of Type 2 Diabetes Synthesis and Pharmacological Evaluation of Novel Nitrobenzenic Thromboxane Modulators asAntiplatelet Agents Acting on Both the Alpha and Beta Isoforms of the Human ThromboxaneReceptor Discovery of New Antitubercular OxazolylThiosemicarbazones Structure-Based Design of Spiro-oxindoles asPotent, Specific Small-Molecule Inhibitors of theMDM2−p53 Interaction Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1.Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles Refining the Multiple Protein Structure Pharmacophore Method: Consistency across ThreeIndependent HIV-1 Protease Models Structural Changes and Binding Characteristicsof the Tetracycline-Repressor Binding Site onInduction Mapping the Melatonin Receptor. 7. Subtype Selective Ligands Based on β-SubstitutedN-Acyl-5-methoxytryptamines and β-Substituted N-Acyl-5-methoxy-1-methyltryptamines Design and Synthesis of Novel Sulfonamide-Containing Bradykinin hB2 Receptor Antagonists. 1.Synthesis and SAR of α,α-Dimethylglycine Sulfonamides Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and MinimalCross-Kinase Activity Dependence of Molecular Properties onProteomic Family for Marketed Oral Drugs Inhibition of Carbonic Anhydrase-II by Sulfamate and Sulfamide Groups: An InvestigationInvolving Direct Thermodynamic Binding Measurements A Novel Series of Potent and Selective PDE5 Inhibitors with Potential for High andDose-Independent Oral Bioavailability Discovery of a Novel Family of SARS-CoV Protease Inhibitors by Virtual Screening and3D-QSAR Studies Detailed Description of the Conformation and Location of Membrane-Bound Erythromycin AUsing Isotropic Bicelles Finding a Needle in a Haystack: Development of a Combinatorial Virtual Screening Approachfor Identifying High Specificity Heparin/Heparan Sulfate Sequence(s) Structure−Activity Relationship Studies on a Series of Novel, Substituted1-Benzyl-5-phenyltetrazole P2X7 Antagonists Effect of Various Pyrimidines Possessing the 1-[(2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl]Moiety, Able To Mimic Natural 2‘-Deoxyribose, on Wild-type and Mutant Hepatitis B VirusReplication Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines: High Affinity and Selective A2BAdenosine Receptor Antagonists Fancy Bioisosteres: Novel Paracyclophane Derivatives As Super-Affinity Dopamine D3Receptor Antagonists 6-N,N-Dimethylamino-2,3-naphthalimide: A New Environment-Sensitive Fluorescent Probe inδ- and μ-Selective Opioid Peptides Multivalent Antimicrobial Peptides from aReactive Polymer Scaffold Biological Evaluation, Chelation, and Molecular Modeling Studies of Novel Metal-ChelatingInhibitors of NF-κB-DNA Binding: Structure Activity Relationships Role of Tyr356(7.43) and Ser190(4.57) in Antagonist Binding in the Rat β1-Adrenergic Receptor Imino-tetrahydro-benzothiazole Derivatives as p53 Inhibitors: Discovery of a Highly Potent inVivo Inhibitor and Its Action Mechanism Isatin Compounds as Noncovalent SARSCoronavirus 3C-like Protease Inhibitors Novel Analogues of Degarelix Incorporating Hydroxy-, Methoxy-, and Pegylated-Urea Moietiesat Positions 3, 5, 6 and the N-Terminus. Part III DNA Binding Affinity of Bisguanidine and Bis(2-aminoimidazoline) Derivatives with in VivoAntitrypanosomal Activity QSAR/QSPR and Proprietary Data

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