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Development and Characterization of Biphenylsulfonamides as Novel Inhibitors of BoneResorption
Discovery of 3-Methyl-N-(1-oxy-3‘,4‘,5‘,6‘-tetrahydro-2‘H-[2,4‘-bipyridine]-1‘-ylmethyl)benzamide(ABT-670), an Orally Bioavailable Dopamine D4 Agonist for the Treatment of ErectileDysfunction
Subtle Side-Chain Modifications of the Hop Phytoestrogen 8-Prenylnaringenin Result inDistinct Agonist/Antagonist Activity Profiles for Estrogen Receptors α and β
Novel Heterobivalent Tacrine Derivatives as Cholinesterase Inhibitors with Notable SelectivityToward Butyrylcholinesterase
2-Triazole-Substituted Adenosines: A New Class of Selective A3 Adenosine Receptor Agonists,Partial Agonists, and Antagonists
C-(4,5,6-Trimethoxyindan-1-yl)methanamine: A Mescaline Analogue DesignedUsing a Homology Model of the 5-HT2A Receptor.
Tricyclic Pyrazoles. 4. Synthesis and Biological Evaluation of Analogues of the Robust andSelective CB2 Cannabinoid Ligand 1-(2‘,4‘-Dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide
Discovery of HIV-1 Protease Inhibitors with Picomolar Affinities IncorporatingN-Aryl-oxazolidinone-5-carboxamides as Novel P2 Ligands
Engineering of a VPAC2 Receptor Peptide Agonist To Impart Dipeptidyl Peptidase IV Stabilityand Enhance in Vivo Glucose Disposal
Catalysis of Organic Reactions By John R. Sowa, Jr. CRCPress, Taylor and Francis, Boca Raton, FL. xv + 574 pp. 16 ×23.5 cm. 2006. ISBN 978-0-8247-2729. £115.00.
Adenosine Mimetics as Inhibitors of NAD+-Dependent Histone Deacetylases, from Kinase toSirtuin Inhibition
Proteomics in Drug Research Edited by Michael Hamacher,Katrin Marcus, Kai Stühler, André van Hall, Bettina Warscheid,and Helmut E. Meyer. Wiley-VCH Verlag, Weinheim, Germany. 2006. xxi + 362 pp. 17.5 × 25 cm. ISBN 3-527-31226-9. $185.00.
Structure−Activity Relationship Analysis of the Selective Inhibition of Transglutaminase 2 byDihydroisoxazoles
Progressive Docking: A Hybrid QSAR/Docking Approach for Accelerating In Silico HighThroughput Screening
Paclitaxel Prodrugs: Toward Smarter Delivery of Anticancer Agents
Low-Calcemic, Highly Antiproliferative, 1-Difluoromethyl Hybrid Analogs of the NaturalHormone 1α,25-Dihydroxyvitamin D3: Design, Synthesis, and Preliminary Biological Evaluation
Identification of the Brominated Flame Retardant 1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexaneas an Androgen Agonist
Synthesis of Essential Drugs By Ruben Vardanyan and VictorHruby. Elsevier, Amsterdam, The Netherlands. 2006. xvi + 617pp. 17 × 24.5 cm. ISBN 10 0-444-52166-6. $240.00.
Fluorinated Conformationally Restricted γ-Aminobutyric Acid Aminotransferase Inhibitors
Profile and Molecular Modeling of 3-(Indole-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5dione (1) as a Highly Selective VEGF-R2/3 Inhibitor
Discovery of Oxadiazoyl Tertiary CarbinamineInhibitors of β-Secretase (BACE-1)
The Sigma-RBI Handbook of Receptor Classification andSignal Transduction. Fifth Edition Edited by Keith J.Watling. Sigma-RBI, Natick, MA. 2006. viii + 376 pp. 23.5 ×218 cm. ISBN 0964054841. $60.00.
Elucidation of the Bioactive Conformation of the N-Substitutedtrans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Class of μ-Opioid Receptor Antagonists
Synthesis, Characterization, and in Vitro Antitumor Properties ofTris(hydroxymethyl)phosphine Copper(I) Complexes Containing the NewBis(1,2,4-triazol-1-yl)acetate Ligand
Isoprenoid Biosynthesis as a Drug Target: Bisphosphonate Inhibition of Escherichia coli K12Growth and Synergistic Effects of Fosmidomycin
Design and Synthesis of N-(3,3-Diphenylpropenyl)alkanamides as a Novel Class of High-AffinityMT2-Selective Melatonin Receptor Ligands
Protein-Ligand Binding Affinity Predictions by Implicit Solvent Simulations: A Tool for LeadOptimization?
High Antiplasmodial Activity of Novel Plasmepsins I and II Inhibitors
Design and Evaluation of Hydroxamate Derivatives as Metal-Mediated Inhibitors of a ProteinTyrosine Kinase
The ACS Style Guide. 3rd Edition Edited by Anne M.Coghill and Lorrin Garson. Oxford University Press, New York.2006. xiv + 430 pp. 18 × 20.5 cm. ISBN 13: 978-0-8412-3999-9. $41.70.
Interpreting Steep Dose-Response Curves inEarly Inhibitor Discovery
Pharmacokinetics and Metabolism in Drug Design. Methodsand Principles in Medicinal Chemistry. Volume 31. SecondRevised Edition By Dennis A. Smith, Han van de Waterbeemd, and Don K. Walker. Wiley-VCH, Weinheim, Germany.2006. xix + 187 pp. 17.5 × 24.5 cm. ISBN 3527313680.$125.00.
Synthesis and Pharmacological Evaluation of Novel Octahydro-1H-pyrido[1,2-a]pyrazine asμ-Opioid Receptor Antagonists
Design and Synthesis of Novel Derivatives of the Muscarinic Agonist Tetra(ethyleneglycol)(3-methoxy-1,2,5-thiadiazol-4-yl)[3-(1-Methyl-1,2,5,6-tetrahydropyrid-3-yl)-1,2,5-thiadiazol-4-yl] Ether (CDD-0304): Effects ofStructural Modifications on the Binding and Activity at Muscarinic Receptor Subtypes andChimeras
Automatic and Efficient Decomposition of Two-Dimensional Structures of Small Molecules forFragment-Based High-Throughput Docking
Lead Compounds for Antimalarial Chemotherapy: Purine Base Analogs Discriminate betweenHuman and P. Falciparum 6-Oxopurine Phosphoribosyltransferases
Frontiers in Drug Design and Discovery. Volume 2 Editedby Gary W. Caldwell, Atta-ur-Rahman, Michael R. D'Andrea,and M. Iqbal Choudhary. Bentham Science Publishers Ltd.,Hilversum, The Netherlands. 2006. vi +365 pp. 16.5 × 25 cm.ISBN 90-77527-03-6. $130.00.
Biological Activity of Designed Photolabile Metal Nitrosyls: Light-Dependent Activation ofSoluble Guanylate Cyclase and Vasorelaxant Properties in Rat Aorta
Aminodeoxychorismate Synthase Inhibitors from One-Bead One-Compound CombinatorialLibraries: “Staged” Inhibitor Design
Annual Review of Biochemistry. Volume 75 Edited by RogerD. Kornberg, Christian R. H. Raetz, James E. Rothman, andJeremy W. Thorner. Annual Reviews, Palo Alto, CA. 2005. x+ 892 pp. 15 × 25 cm. ISBN 0-8243-0875-1. $208.00.
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