The methanolic extract from the leaves of Kalanchoestreptantha (Crassulaceae) afforded anew kaempferol3-O-β-xylopyranosyl-(1→2)-α-rhamnopyranoside7-O-(4‘‘‘‘-O-acetyl-α-rhamnopyranoside), named 4‘‘‘‘-acetylsagittatin A (1), and theknown sagittatin A (2). The structureswere determined by 1H-1H and1H-13C COSY NMR and FAB mass spectroscopy andconfirmedby analysis of the peracetylated derivative.