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À propos de : Keenamide A, a Bioactive Cyclic Peptide from the Marine MolluskPleurobranchus forskalii        

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  • Keenamide A, a Bioactive Cyclic Peptide from the Marine MolluskPleurobranchus forskalii
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  • Keenamide A (1), a new cytotoxic cyclic hexapeptide,was isolated from the notaspidean molluskPleurobranchus forskalii. Its structure was determinedby NMR spectral data interpretationand chiral amino acid analysis. Keenamide A (1)exhibited significant activity against theP-388, A-549, MEL-20, and HT-29 tumor cell lines, but was inactive whenevaluated againstthe D6 and W2 Plasmodium falciparum malarialclones.
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