| Abstract
| - 2,6-Dimethylheptyl sulfate (1) was isolated for thefirst time from a marine ascidian fromPolicitor adriaticus Drasche (class Ascidiacea, orderAplousobranchiata, family Polycitoridae).In this work, the absolute stereochemistry at C-2 of 1was determined by 1H-NMR analysis ofits (+)- and (−)-methoxy(trifluoromethyl)phenylaceticacid (MTPA) esters (Mosher's method).The distribution of 1 was investigated among the threeorders (Aplousobranchiata, Phlebobranchiata, and Stolidobranchiata) of the class Ascidiacea.Compound 1 showed cytotoxicity(LC50 = 17.8 μg/mL) in the Artemia salinabioassay and was not toxic (not toxicity at 100 μg/mL) in a fish (Gambusia affinis) lethalityassay.
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