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À propos de : New Macrodiolide Antibiotics, 11-O-Monomethyl- and11,11‘-O-Dimethylelaiophylins, from Streptomyces sp. HKI-0113 and HKI-0114        

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  • New Macrodiolide Antibiotics, 11-O-Monomethyl- and11,11‘-O-Dimethylelaiophylins, from Streptomyces sp. HKI-0113 and HKI-0114
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  • Elaiophylin (1) and two new methyl derivatives, 11-O-monomethylelaiophylin (2) and 11,11‘-O-dimethylelaiophylin (3), were isolated from the mycelium cake of Streptomyces strains HKI-0113 andHKI-0114. The structures of 2 and 3 were determined by mass spectrometric and NMR investigations.Compounds 2 and 3 display antimicrobial and moderate cytotoxic activities.
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