| Abstract
| - A new aminosteroid, 3β-amino-22,26-epiminocholest-5-ene named sarachine (1), and two knownflavonoids, eriodictyol (2) and 7-O-β-d-glucopyranosyl-eriodictyol (3), were isolated from theleaves of Saracha punctata. The alkaloid was found to inhibit the growth of Leishmaniabraziliensis promastigotes (100% at 25 μM) and of Trypanosoma cruzi epimastigotes in culture(50% at 25 μM) and showed a strong in vitro antiplasmodial activity with an IC50 of 25 nM.
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