| Abstract
| - The known compound methyl 2,4-dihydroxy-3,5,6-trimethylbenzoate (1) and three new related metabolites,which we have named mortivinacins A (2), B (3), and C (4), were identified as metabolites of the fungusMortierella vinacea. Nicotinic acid (5) was also encountered. This isolate of M. vinacea was obtainedfrom an Aspergillus flavus sclerotium during field studies of sclerotium longevity in soil. Compounds1−5 were isolated by chromatographic fractionation of organic extracts from M. vinacea solid−substratefermentation cultures, and the structures were assigned by analysis of NMR and MS data. Compounds1, 2, and 5 were responsible for the antibacterial and antifungal activities of the extract.
|
