| Abstract
| - Microbial transformation studies of the synthetic antifungal alkaloid benzosampangine (1) have revealedthat 1 is metabolized by a number of microorganisms. Using a standard two-stage fermentation techniqueAbsidia glauca (ATCC 22752), Cunninghamella blakesleeana (ATCC 8688a), Cunninghamella species(NRRL 5695), Fusarium solani f. sp. cucurbitae (CSIH #C-5), and Rhizopogon species (ATCC 36060) eachproduced a β-glucopyranose conjugate of benzosampangine (2). The identity of 2 was established on thebasis of spectroscopic data.
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