| Abstract
| - Four new alkaloids (1−4) were isolated from the marine sponge Axinella brevistyla, and their structureswere determined on the basis of spectroscopic analysis. The alkaloids 1−4 were antifungal against theyeast Saccharomyces cerevisiae at <1.0, <1.0, 30, and 100 μg/disk, respectively. Compounds 1−3 alsoexhibited cytotoxicity against L1210 cells with IC50 values of 1.1, 0.66, and 2.5 μg/mL, respectively.
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