Documentation scienceplus.abes.fr version Bêta

À propos de : Continuing Studies on the Cyanobacterium Lyngbya sp.: Isolation andStructure Determination of 15-Norlyngbyapeptin A and Lyngbyabellin D        

AttributsValeurs
type
Is Part Of
Subject
Title
  • Continuing Studies on the Cyanobacterium Lyngbya sp.: Isolation andStructure Determination of 15-Norlyngbyapeptin A and Lyngbyabellin D
has manifestation of work
related by
Author
Abstract
  • Re-collections of the cyanobacterium Lyngbya sp. have yielded two more members of the lyngbyapeptinand lyngbyabellin families. The gross structures of 15-norlyngbyapeptin A (1) and lyngbyabellin D (3)were deduced through standard 2D NMR techniques, with the absolute configuration of both elucidatedthrough degradation and comparison with commercially available and synthetic standards. Degradationto the α-amino acid and NOE correlations determined the absolute and relative configuration of the4-amino-3-hydroxy-5-methylhexanoic acid unit in 3. Lyngbyabellin D (3) displayed an IC50 value of0.1 μM against the KB cell line.
article type
is part of this journal



Alternative Linked Data Documents: ODE     Content Formats:       RDF       ODATA       Microdata