| Abstract
| - Two new caprolactones, (R)-10-methyl-6-undecanolide (1) and (6R,10S)-10-methyl-6-dodecanolide (2), wereidentified in the lipid extract of a marine streptomycete (isolate B6007). Their structures were proposedon the basis of GC−MS experiments and proved by synthesis. The absolute configuration of the compoundswas established by comparison of the natural and synthetic stereoisomers using chiral gas chromatography.These caprolactones show a moderate phytotoxicity and a promising activity against cancer cells withconcomitant low general cytotoxicity.
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