| Abstract
| - Bioassay-directed fractionation of a methyl ethyl ketone extract of the roots of Endlicheria aff. resultedin the isolation of four new neolignans (1−4) and eight known compounds, namely, canellin A (5), canellinC (6), 3‘-methoxyguianin (7), (7S,8R,1‘S,5‘S,6‘R)-Δ2‘,8‘-3‘,6‘-dihydroxy-5‘-methoxy-3,4-methylenedioxy-4‘-oxo-8.1‘,7.5‘-neolignan (8), armenin-B (9), dillapiole (10), 1-allyl-2,6-dimethoxy-3,4-methylenedioxybenzene (11), and ω-hydroxyisodillapiole (12). The structures of the new compounds (1−4) were establishedas (7S,8R,1‘S,5‘S,6‘R)-Δ2‘,8‘-5‘,6‘-dihydroxy-3‘-methoxy-3,4-methylenedioxy-4‘-oxo-8.1‘,7.5‘-neolignan,(7S,8R,1‘S,5‘S,6‘R)-Δ2‘,8‘-3‘,5‘,6‘-trihydroxy-3,4-methylenedioxy-4‘-oxo-8.1‘,7.5‘-neolignan, 2,4-dimethoxy-5,6-methylenedioxy-1-(2-propenyl)benzene, and 2,6-dimethoxy-3,4-methylenedioxycinnamyl alcohol, respectively, on the basis of spectroscopic interpretation.
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