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À propos de : Microbial O-Demethylation, Hydroxylation, Sulfation, and Ribosylation of a XanthoneDerivative from Halenia elliptica        

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  • Microbial O-Demethylation, Hydroxylation, Sulfation, and Ribosylation of a XanthoneDerivative from Halenia elliptica
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  • 1-Hydroxy-2,3,5-trimethoxyxanthone (1), one of the major xanthone derivatives isolated from Halenia elliptica, wasbiotransformed by two fungi, Trichothecium roseum and Paecilomyces marquandii. Transformation of 1 by T. roseumgave 1,5-dihydroxy-2,3-dimethoxyxanthone (2), 5-O-sulfate-1-hydroxy-2,3-dimethoxyxanthone (3), 5-O-sulfate-1-hydroxy-2,3,7-trimethoxyxanthone (4), 5-O-β-ribofuranosyl-1-hydroxy-2,3-dimethoxyxanthone (5), and 1,5,6-trihydroxy-2,3-dimethoxyxanthone (6). Compound 2 was also formed by P. marquandii. The structures of the isolated compoundswere elucidated by spectroscopic analyses. Among the five microbial-converted compounds, 3, 4, 5, and 6 are newcompounds.
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