| Abstract
| - Two new neolignans, piperkadsin A (1) and piperkadsin B (2), as well as 11 known neolignans, three known alkaloids,the highly oxygenated compound (+)-crotepoxide, and stigmasterol were isolated from the stems of Piper kadsura.The anti-inflammatory activities of these compounds were evaluated. Compounds 1, 2, futoquinol (3), piperlactam S(4), and N-p-coumaroyl tyramine (5) showed potent inhibition of PMA-induced ROS production in humanpolymorphonuclear neutrophils with IC50 values 4.3 ±1.0, 12.2 ± 3.2, 13.1 ± 5.3, 7.0 ± 1.9, and 8.4 ± 1.3 μM,respectively.
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