Documentation scienceplus.abes.fr version Bêta

À propos de : Twisted Amides as Selective Acylating Agents for HydroxylGroups under Neutral Conditions: Models for Activated Peptidesduring Enzymatic Acyl Transfer Reaction        

AttributsValeurs
type
Is Part Of
Subject
Title
  • Twisted Amides as Selective Acylating Agents for HydroxylGroups under Neutral Conditions: Models for Activated Peptidesduring Enzymatic Acyl Transfer Reaction
has manifestation of work
related by
Author
Abstract
  • The highly twisted amide 2 served as a selectiveacylating agent for diols under neutral conditions.The reaction of primary−secondary diols with 2 led tothe corresponding primary alkyl monopivalates. For diols containing alcoholic and phenolic hydroxylgroups, alcoholic hydroxyl groups wereselectively acylated under neutral conditions, whereas, the oppositeselectivity was observed underbasic conditions, similar to the cases using acyl halides or acidanhydrides. Although 1 and 3were unreactive to alcohols, 5−10 havingsubstituent groups at C-4 were reactive to alcohols togive the corresponding acetates or benzoates.
article type
is part of this journal



Alternative Linked Data Documents: ODE     Content Formats:       RDF       ODATA       Microdata