| Abstract
| - The chair and twist-chair conformations of seven-membered ringsare classified as a function ofthe signs of their endocyclic torsion angles. The conformationalanalysis (MM3) of the methoxy-and methyloxepanes 1−6 used as patterns allows the studyand classification of the different typesof hydrogen orientation in the seven-membered saturated heterocycles.General principles areestablished, allowing the prediction of the stability of the differenttwist-chair conformations as afunction of the substituent type, its position in the ring, and thetype of hydrogen atom that hasbeen substituted. These results are extended to the 1,4-dioxepanederivatives 7−13 and arecompared with experimental data.
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