| Abstract
| - A chemoenzymatic strategy has been developed for the synthesis ofbastadins 2, 3, and 6. Therequisite dimeric dityrosine and isodityrosine building blocks weresuccessfully prepared by oxidativeC−C and C−O phenolic coupling of mono- and dihalogenatedderivatives of tyrosine and tyramineusing horseradish and soybean peroxidases. By carefullycontrolling the experimental parameters,the requisite synthons may now be prepared in synthetically usefulyields without the exhaustiveprotection and deprotection of the sensitive functionalgroups.
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