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À propos de : Ascosalipyrrolidinone A, an Antimicrobial Alkaloid, from theObligate Marine Fungus Ascochyta salicorniae        

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  • Ascosalipyrrolidinone A, an Antimicrobial Alkaloid, from theObligate Marine Fungus Ascochyta salicorniae
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  • From the green alga Ulva sp., the endophytic and obligate marine fungus Ascochyta salicorniaewas isolated. A. salicorniae was mass cultivated and found to produce the unprecedented andstructurally unusual tetramic acid containing metabolites ascosalipyrrolidinones A (1) and B (2).Additionally, the new natural product ascosalipyrone (3) and the known metabolites 4 and 5 wereobtained. Ascosalipyrrolidinone A (1) has antiplasmodial activity toward Plasmodium falciparumstrains K1 and NF 54, as well as showing antimicrobial activity and inhibiting tyrosine kinasep56lck.
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