Documentation scienceplus.abes.fr version Bêta

À propos de : Efficient Kinetic Resolution in the Asymmetric Hydrosilylation ofImines of 3-Substituted Indanones and 4-Substituted Tetralones        

AttributsValeurs
type
Is Part Of
Subject
Title
  • Efficient Kinetic Resolution in the Asymmetric Hydrosilylation ofImines of 3-Substituted Indanones and 4-Substituted Tetralones
has manifestation of work
related by
Author
Abstract
  • Kinetic resolution of the N-methyl imines of 3-substituted indanones and 4-substituted tetralonescould be accomplished by hydrosilylation with a chiral titanocene catalyst. N-Methyl imines of4-substituted tetralones were resolved to yield, after hydrolysis of the unreacted starting materials,ketones with high ee's and the amine products with high diastereomeric and enantiomeric purity.The utility of this process was demonstrated in the synthesis of sertraline.
article type
is part of this journal



Alternative Linked Data Documents: ODE     Content Formats:       RDF       ODATA       Microdata